MADUIKE CHIEHIURA ONWUBIKOEZIEBE

MADUIKE CHIEHIURA ONWUBIKOEZIEBE

PROFESSOR

Biography

MADUIKE C. O. EZEIBE

 1.   Personal Data.

 

Name:                                 Maduike Chiehiura OnwubikoEzeibe.                

Nationality:                          Nigerian.
 

Marital status:                     Married.

Contact Address:               Department of Veterinary Medicine,

 

                                            Michael Okpara University of Agriculture,

                                            Umudike, AbiaState.

 

2. Educational institutions attended and qualifications obtained:

University of Nigeria, Nsukka,PhD. 2002.

University of Nigeria, Nsukka, MSc. 1994.

University of Nigeria, Nsukka  DVM, 1986  with distinction in Veterinary  Public health and Jurisprudence

College of Veterinary Suegeons Nigeria,   MCVSN,  2004.

College of Veterinary surgeons Nigeria,    FCVSN,    2015.

 

3. Area of specialization:Vet. clinicalvirology.

 

4. Accademic Prizes/ Grants Won:

 i)       Best student,  Department of Veterinary Microbiology, Pathology , Public health and Jurisprudence,UNN (1985).

ii)       Best student in Veterinary clinics, UNN (1986).

iii)      2011, M. C. O. Ezeibe  Listed as one of  world`s scientific experts in viral  haemagglutination tests  by Lambertvile, New Jersey, U. S. A. Labome.org    2011.

iv)      Presidential Standing Committee on Inventions and Innovations grant for invention of Medicinalsynthetic Aluminium – magnesium      silicate(Nanoparticles)– Antiviral medicine and adjuvant for chemotherapeutics   (2011).

 

5.Thesis/Dissertations written:

          M. C. O. Ezeibe (1986). Haemagglutination – Inhibition test for differential  diagnosis of infections of Peste des Petits Ruminant Virus and Rinderpest Virus (DVM project).

          M. C. O. Ezeibe (1994). Clinical and virus excretion studies on PPR disease (MSc. dissertation).

          M. C. O. Ezeibe (2002). Clinical studies on Canine distemper disease of dogs     (PhD. thesis).

          M. C. O. Ezeibe (2015).Studies of effects of Aluminum-magnesium silicate and   B-vitamins on actions of Chloroquine, for treatment of plasmodium infections,

          with mice as models (FCVSN thesis).

 

6. Conferences Attended.

          Second Biennial conference of the African small ruminant research network, Tanzania (1992).Haemagglutination – inhibition technique for definitive diagnosis   of Peste des Petits Ruminants virus specific antibody.

          19th Annual conference of Nigerian society for animal production, Benin city (1994).Carrier status of West African Dwarf goats that recovered from Peste des   Petits Ruminants disease.

          32nd Annual congrees of Nigerian Veterinary Medical Association, Vom (1995).   Managment of tick paralysis in a dog in Nigeria.

          22nd Annual conference of Nigerian society for animal production, Bauchi (1997).Early diagnosis of Infectious bursal disease, using the first clinical signs of    the disease in chicks.

          5th Annual conference of Agricultural Extension Society of Nigeria, Nsukka (1999).PPR disease of sheep and goats – Need for public education.

          36th Annual conference of Nigerian Veterinary Medical Association, Kaduna (1999).Prevalence of PPR haemagglutinin in farm goats in Nsukka.

          25th Annual conference of Nigerian society for animal production, Umudike (2000).Evaluation of virus titre of Newcastle Disease vaccine (laSota) imported    into Nigeria.

          29th Annual conference of Nigerian society for animal production, Sokoto (2004).Detection of virus of PPR in faeces of sick and recovered goats.

          International conference on Research and Development, Accra (2008).Effect of a  synthesized Aluminum – magnesium silicate on Avian InfluenzaVirus subtype        H5N1.

5thworld congress on Virology, Atlanta, USA, 7th- 9th December, 2015. Medicinal synthetic Aluminum-magnesium silicate{Al4(SiO4)3 + 3Mg2SiO4 → 2Al2Mg3(SiO4)3} – Ahighlyactiveanti-retroviral medicine.

2nd  International conference and exhibition on Pharmacology and Ethnopharmacology, Chicago, USA, 2nd -4th May, 2016. Stabilizing antimicrobials with the Medicinal synthetic Aluminum-magnesium silicate {Al4(SiO4)3 + 3Mg2SiO4 → 2Al2Mg3(SiO4)3},to enhance their efficacy, for prevention and treatment of resistant infections.

 8th world Virology congress, San Antonio, USA, 28th- 30th November, 2016.  Medicinal synthetic Aluminum-magnesium silicate{Al4(SiO4)3 + 3Mg2SiO4 → 2Al2Mg3(SiO4)3} – Effective treatment for HIV/AIDS.

 

7. Academic/Professional Career:

Institutions:                      Postions held with Dates:

Anambra state Ministry of Agriculture                 Vet. officer(National Youths Service Corps)  1986-1987.

Sal Vet. Services Nig. Ltd. Aba                            Private practice                                                 1987- 1992.

University of Nigeria, Nsukka                             Graduate Assistant                                           1992 – 1994.

University of Nigeria, Nsukka                             Lecturer II                                        1994–2000.

University of Nigeria, Nsukka                             Senior Lecturer      2000 – 2005.

University of Nigeria, Nsukka.                            Reader      2005 -    2011.

University of Nigeria, Nsukka                             Professor     2011 - 2013.

Michael Okpara Univ. of Agric., Umudike           Professor2013-   Date

 

8. Administrative positions held:

a)  Head of Department of Veterinary Medicine, MOUAU, 2013 – date.

b)Head, Department of Vet, Medicine, UNN, 2011 – 2012.

c) Head , Department of Vet. Medicine, UNN, 2005 - 2008.

d) Deputy, Director Vet. Teaching hospital, UNN, 2005 – 2006.

e) Chairman, Faculty of Vet. Medicine farm committee,UNN, 2003 – 2005.

f) Cordinator , Faculty courses,UNN, 2002 – 2004.

g) Chairman, Faculty Time table committee, UNN, 2000 – 2002.

h) Cordinator of Vet. clinics, UNN, 1994 – 1995.

 

9. Membership of professional bodies and positionsheld.

a) Nigerian Veterinary Medical Association (NVMA).

i)  Deputy Editor Nigerian Veterinary journal, 2001 – 2005.

 ii)  Second National vice president,  2005 – 2009.

b) Nigerian Society for Animal Production(NSAP): Chairman, Enugu state chapter                    2002 – 2009.

 

10. Courses taught.

Veterinary Medicine.

 i  Infectious and non  - infectious Diseases of Laboratory and Zoological animals.

ii  Infectious   Diseases of Small Ruminants.

Veterinary Clinics.

Practical clinics to DVM students.

Postgraduate vet. Medicine.

i Nervous and Respiratory Diseases of different species of animals.

ii Diagnostic Techniques for confirmation of viral diseases.

 

11. Major researches completed.

a). Synthesis of the Medicinal synthetic Aluminum –magnesium silicate from Aluminum silicate and Magnesium silicate found in Nigeria.

b). Tests of effects of  the Medicinal synthetic Aluminum – magnesium silicateon viruses  that cause diseases in chickens.

c). Tests of effects of  theMedicinal synthetic Aluminum – magnesium silicateon viruses  that cause diseases in mammals (PPR virus and Canine parvovirus).

d) . Tests  of effects of the Medicinal synthetic Aluminum – magnesium silicate as adjuvant to anticoccidial activity of Sulphadimidin,to anthelmintic activity of Piparazine citrate,to antibiotic activity of Ampicilline trihydrate and to antimalarial activity of Chloroquine phosphate.

e).Tests of ability of the Medicinal synthetic Aluminum – magnesium silicate to make chemotherapeutics regain  effects against resistant organisms.

f).Antiretroviral  effects of  the Medicinal synthetic Aluminum – magnesium silicate.

12. Current  interest: To teach Vet. graduates to be job creators instead of being   job seekers.

13. Book(s) Edited: Poultry farmers` guide, Agu, V. C. (2010).

 

14. Academic publications/intellectual property.

i ) 68 articles published/accepted by local and international journals.

ii) 11 published conference proceedings.

iii) Three books

iv)  Four registered patents and three others being processed.

 

 15.Postgraduate  researches supervised.

i.             Sanda, M. E. – Some factors that affect weight gain,and humoral immune response of broilers  to Newcastle disease  vaccination in Dekina Local Government Area, Kogi state, Nigeria (Ph.D,2011).

ii. Ijabo, O. – Effects of Aluminum – magnesium silicate on Peste des petits ruminants  virus  and on Newcastle disease virus (M. Sc.,2006).

iii. Okoroafor, O. N. – Prevalence of antibodies to Egg drop syndrome 76 virus in chickens with low egg productivity in Nsukka and effect of Aluminum – magnesium silicate on the virus

(M. Sc.,2006).

iv. Nwaigwe, A. N. – Effect of Aluminum – magnesium silicate on Canine Parvovirus infection

 ( M. Sc.,2010).

v. Egbuji, A. N. – Effects of  Aluminum – magnesium silicate on  H5N1,Avian Influenza Virus (M.Sc.2011).  

vi . Animoke, P. C. – Seroprevalence of antibodies of IBD virus in Day old  chicks hatched in Southern Nigeria and effects of vitamine B complex on immune response of chicks to IBD vaccination (M. Sc. 2011).

vii. Elendu - Eleke, N.P. – Effect of Aluminum – magnesium silicate on antiplasmodial activity of Chloroquine phosphate (M. Sc.2014 ).

Viii.  Ogunniran,T.  - Assessment of virus titre and seroconversion abilities of five  Infectious Bursal disease virus vaccine brands used in Nigeria (M. Sc. 2014).

ix. Ezeobele,F. O.K.Effects  of a synthetic Aluminum – magnesium silicate on antimicrobial activity of Ampicillin trihydrate,  against resistant Escherichia coliisolate(M. Sc. 2015).

x. Nwankwo, I. A.Immune response of chicks to different units of the local Infectious bursa disease vaccine (M.Sc, 2016).

 

xi. Ezeala, I . E. Characterization  of strains of  Newcastle disease virus involved in outbreaks of the disease in Nsukka, Enugu state- Nigeria. (Completed M. Sc. research).

 

 16. Micellaneous.

External examiner,Department of Veterinary Medicine, University of Agriculture,

Makurdi, 2005-2006.

External examiner,Department of Veterinary Medicine, University of Abuja, 2015-date.

External examiner,Department of Veterinary Medicine (PhD) University of Agriculture,

Abeokuta (2017).

 Staff Adviser National Association of Veterinary Medical students , Nigeria, 2006 – 2007.

Staff Adviser Associaton of Vet. medicalstudents UNN, 2007 – 2013.

 

17. Referees. 

Professor B,N, Mba,  Provost, federal college of Education Ehamufu .

Professor C. O. Nwosu,  Dean Faculty of Veterinary Medicine, University of Nigeria, Nsukka

 

List of Publications and Patents.

 

A.   Articles.

1.       Wosu, L.O. and Ezeibe, M.C.O. (1991). Haemagglutination-Inhibition technique for definitive diagnosis of PPR virus specific antibody.Biomedical Letters 48:173-177.

2.       Wosu, L.O. and Ezeibe, M.C.O. (1992). Haemagglutination-Inhibition technique for definitive diagnosis of Rinderpest virus specific antibody.Better:Landwirtsch.Vet. Med. 30:299-304.

 3.       Ezeibe, M.C.O. (1997). Observations on natural outbreaks of Aspergilloisis in chickens in Nsukka, Enugu StateNigeria. Nig. Vet. J. 18(2):245-248.

 4.       Ezeibe, M.C.O. and Wosu, L.O. (1997). Clinical signs of PRR in natural field outbreaks. Nig. Vet. J. 18(2): 247-252.

 5.       Ezeibe, M.C.O. and Wosu, L.O. (1997). Reproductive ability of female goats, following recovery from PPR. Small Ruminant Research. 187-189.

 6.       Ezeibe, M.C.O. (1998). Management of vaccine-induced infectious Bursal disease in Chicks with antibiotics and antidiarrhoeics. Nig. J. Anim. Prod. 24(2): 86-89.

 7.       Ezeibe, M.C.O. (1998). Management of different stages of field outbreaks of Gumboro disease. Proc. WASAP. Conf. Abeokuta. Pp 82-83.

 8.       Ezeibe, M.C.O. (1998). Giardiasis in a flock of rabbits in Nigeria.  Proc. WASAP Conf. Abeokuta. Pp. 81.

 9.       Ezeibe, M.C.O. (1998). A case of Aspergillosis in mature Turkeys. Proc. WASAP Conf. Abeokuta. Pp. 86.

 10.     Ezeibe, M.C.O. (1999). PPR disease of sheep and goats-need for public education. Proc. 5th Ann. Conf. Agric. Ext. Soc. Nig. Pp.30-33.

 11.     Ezeibe, M.C.O. and Ozoemena, U.B. (2000). Evaluation of virus titre and seroconversion ability of foreign Newcastle vaccines [IaSota] imported into  Nigeria. Proc. NSAP. Pp 296.298.

 12.     Ezeibe, M.C.O. and Agwu, U.K. (2000). Seroconversion activities of oil emulsion and water based Newcastle disease vaccines. Proc. 27th Conf. NSAP. Pp. 70-71.

 13.     Ezeibe, M.C.O. (2000). Reoccurrence of PPR in Kids. Nig. Vet. J. 21:27-29.

 14.     Ezeibe, M.C.O. (2000). Canine distemper: A review. Studies and Research in Vet. Medicine 8:99-101.

 15.     Ezeibe, M.C.O. and Wosu, L.O. (2000). Ondersteport Canine distemper vaccine and measles vaccine protect Nigerian dogs against local isolate of Canine distemper virus. Nig. Vet. J. 23(2):51-55.

 16.     Ezeibe, M.C.O. (2001). Haemaggluitination technique for detection of Newcastle disease virus in live Chickens. Nig. Vet. J. 22(1):37- 41.

 17.     Ezeibe, M.C.O. (2003). Clinical Manifestations of Canine distemper in Nigerian Dogs infected with local isolate of Canine distemper virus. Nig. Vet. J. 24(1):44-47.

 18.     Ezeibe, M.C.O. (2003). Indirect haemagglutination-Inhibition (HI) test for Canine distemper. Studies and Researches in Vet. Medicine. Supplement (1):11-15.

 19.     Ezeibe, M.C.O., Wosu, L.O. and Erumaka, I.G. (2004). Standardization ofhaemagglutination test for PPR. Small Ruminant Research 51:269-272.

 20.     Ezeibe, M.C.O. and Akpa, E.C. (2004). Presence of None specific haemagglutinins in sera of some Animal species found in Nigeria. International J. Agric. Biol. Sc.3 : 29 – 31.

 21.     Ezeibe, M.C.O. and Anyalewechi, O.C. (2004). Canine distemper associated with generalized Oedema in Nigerian dogs. Trop. Vet. 22(2):53-56.

 22.     Ezeibe, M.C.O. and Ngene, A.A. (2004). Agglutination of chicken red blood cells by tissue homogenate of goats naturally infected with PPR virus.Proc. 29th Ann. Conf. NSAP. Pp. 56-57.

 23      Ezeibe, M.C.O. (2004).Detection of  Peste des petitis Ruminants virus in faeces of sick and recovering goats ,29th Ann. Conf. NSAP. Pp. 89-91.

 24.     Ezeibe, M.C.O. (2004). Admacine® .Research and National Development Proc. Distinguished LecturerP.G. School U.N.N. Pp. 104-105.

 25.     Ezeibe, M.C.O. (2004). Francoccine®. Research and National Development Proc. Distinguished Lecturer P.G. School U.N.N. Pp. 105-106.

 26.     Ezeibe, M.C.O. (2004). Chi-travite®. Research and National Development Proc.           Distinguished Lecturer P.G. School U.N.N. P. 106.

 27.     Ezeibe, M.C.O. (2005). Canine distemper disease in Nigerian local dogs. Veterinary Records. 156:840-842.

 28.     Ezeibe, M.C.O. (2005). Symptomatic Management of PPR in West African dwarf goats J. Sust. Agric. Environ. 7(1):11-14.

 29.     Ezeibe, M.C.O. (2005). Relative Resistance of goats to PPR following a sheep to goats transmission of infection. J. Sust. Agric. Environ. 7(1):15-18.

 30.     Ezeibe, M.C.O. and Ndip, E.T. (2005). Red Blood cells Elution Time of Strains of Newcastle disease virus. J. Vet. Sc. 6(4):287-288.

 31.     Ezeibe, M.C.O.; Gbaruko, J.K. and Asuzo, C. (2005). Prevalence of Canine distemper in Nsukka Local Government Area of Enugu State, Nigeria. Vom. J. Vet. Sc.2:52 – 56.

 32.     Shoyinka, S.V.O.; Emehelu, C.O. and Ezeibe, M.C.O. (2005). MalignantMastocytoma in a Nigerian local Dog. Nig. Vet. J. 26(2): 45-50.

 33.     Okoli,I. C.,Opara,M.N.,Anosike, J. C.,Uko, J. U., Agaie,B.M., Garba,H. S.,Jibike,G. I.,Nwosu,C.I.,Nwanta,J. A.,Fayomi,A.,Abiade – Paul, C. U.,Chah,K. F.,Ezeibe, M.C.O. Ajuwape,A.J.P.,Olafa,A.K.,Wehke,S.N.and Oboegbulam,S. I.. (2006). The epizootiology of the highly pathogenic avian influenza prior to the anticipated pandemic of the early twenty first century. Anim. Prod. Res. Adv. 2(1):50-56.

 34.     Obidike,R.I.,Ezeibe, M.C.O.,Omeje,J.T.N and Ugwuomarima,K.G. (2006). Incidence of Peste des petits ruminants haemagglutinins in farm and market goats in Nsukka, Enugu State, Nigeria. Bull.Anim. Hlth. Prod. Afr. 54:148- 150.

 35.     Ezeibe, M.C.O., Eze, I.C., Nwokike, E.C. and Eze, J.I. (2006). Detection and Characterization of Newcastle disease virus from faeces of healthy free-roaming chickens in Nsukka, Nigeria. Trop. Vet. 24:76-80.

 36.     Ezeibe, M.C.O., Okoroafor, O.N., Eze, J.I. and Eze, I.C. (2007). Seroprevalence of egg drop syndrome-76 virus as cause of poor egg productivity of poultry in Nsukka , South East Nigeria. Trop. Anim. Health and Prod. 39:493-505.

 37.     Ezeibe, M.C.O., Eze, I.C., Okoroafor, O.N., Ugonabo, J.A.C., Ngene, A.A. and Eze, J.I. (2008). Persistent detection of Peste de petits ruminants  antigen in faeces of recovered Goats. Trop. Anim Health and Prod. DOI 10.1007/s11250-008-91283.

 38.     Ezeibe, M.C.O., Eze,J. I. and Eze, I.C (2008). Agglutination of red blood cells by Canine distemper virus. Nig. Vet. J. 29(1):57- 62.

 39.     Nwaogu, I.C., Ezeibe, M.C.O. and Ifeduba, O.F. (2008). Effects of Alcohol consumption on homoral immunity in mice. J. App. Anim. Res. 34:181-18

 40     Ezeibe, M. C. O.and Udegbunam, R. I.(2008). Haematology of dogs infected with

Canine distemper virus. Sokoto J. Vet. Sc. 7(2) :32 – 34.

 41.     Ezeibe, M.C.O., Mbuko, I.J., Okoroafor, O.N., Okonkwo, A.C., Animoke, P.C., Orajaka, L.J.E and Ngene, A.A. (2009). In vitro and in vivo effects of Aluminum-magnesium silicate on Infectious bursal disease virus in chiken.Anim. Sc. Rep. 3(4):132-137.

 42.     Ezeibe, M.C.O., Ijabo, O., Okoroafor, O.N., Orajaka, L.J.E., Ukomadu, N.M. Chukwu, O.S. and Ngene, A.A. (2009). Antiviral effects of Aluminum-magnesium silicate on Peste des Petits Ruminants Virus.Anim. Sc. Rep. 3(4):141-147.

 43.     Ezeibe, M.C.O., Eze, J.I., Ijabo, O., Ngene, A.A., Okoroafor, O.N., Ukomadu,N.M., Sanda, E.M., Eze, I.C. and Ugonabo, J.A.C (2010).  Standardization of the PPR haemagglutinin antigen for haemagglutination-inhibition test. J. Appl. Anim. Res.38:113 – 115.

44.     Ezeibe, M.C.O., Eze, J.I., Ijabo, O., Ngene, A.A., Okoroafor, O.N., Ukomadu, N.M., Sanda, E.M., Eze, I.C. and Ugonabo, J.A.C(2010).  Immune response of rats to PPR vaccination.J. Appl. Anim. Res.37(2) : 239 – 240.

 45.     Ezeibe, M.C.O., Okoroafor, O.N., Nwaoga, R.O.,  Ngene, A.A and Eze, J. I.(2010).  Effect of B-vitamins on immune response of dogs to canine distemper vaccination. Anim. Sc. Rep.4 (3) :83 – 86.

 46.     Ezeibe, M.C.O., Okoroafor, O.N., Ijabo, O., Ukomadu, N.M.,  Ngene, A.A and Eze, J. I.(2010).  Haemagglutination-inhibition and Haemagglutination titres of Egg drop syndrome 76 virus treated with Aluminum-magnesium silicate.  Anim. Sc. Rep.4(3) :87 – 90.

 47.Ezeibe, M. C. O., Nwaogu, I. C., Nwaigwe, A. N., Okoroafor, O. N. Eze, J. I. and Ngene, A. A. (2010).  Aluminum – magnesium silicate inhibits canine parvovirus and cures infected dogs .Health.2 (10) : 1215 – 1217.

 48.     Ezeibe, M. C. O.,Okafor,U. C., Okoroafor, O. N.,Eze,J.I., Ngene, A.A.,Animoke,P. C. and Mbuko, I. J.(2011). Effect of Aluminum-magnesium silicate on anticcocidial activity of Sulphadimidine.Tropical Veterinarian. 29 :41  - 44.

49.Ezeibe, M. C. O., Ijabo, O., Uzopuo, C., Okoroafor, O. N., Eze, J. I. Mbuko, I. J., Sanda, M. E., Animoke, P. C. and Ngene, A. A.(2011 ). Effects of Aluminium – Magnesium Silicate on Newcastle disease virus and on recovery of infected chicks.Int. J. Biol. Chem. 5(2): 825 – 829 .

 50.     Ezeibe, M. C. O.,Udegbulam, R. I., Shoyinka, S. V. O. and  Anyalebechi, O. C. (2011). Urinalysis and  Gross pathology of  Nigerian dogs infected with local isolates of the Canine distemper virus. J. Vet. Appl. Sci. 1 (1) : 16 – 20.

 51.     Ezeibe, M. C. O.,Udegbulam, R. I., Etim, N. Eze, J. I. Okoroafor, O. N, Sanda, M. E, Udegbulam, S. O , Ugonabo, J.A. C and  Ngene,A. A (2011). Determination of blood coagulation time for clinical differentiation of Canine distemper from Canine trypanosomosis J. Vet. Appl. Sci. 1 (1) : 27 – 30.

 52.     Ezeibe, M.C.O.,Egbuji, A.N., Eze, J.I., Ijabo, O., Ngene, A. A.,Okoroafor, O. N., Eze, I. C., Ugonabo, J. A. C,. Sanda, M. E. and Mbuko I. J.(2012).Antiviral Effects of a synthetic Aluminum-magnesium silicate on Avian Influenza Virus . Health 4(7) : 429 – 432.

 53.     Ezeibe, M. C. O. ,Elendu – Eleke, N. P., Okoroafor, O. N. and Ngene ,A. A (2012). Adjuvant effect of a synthetic Aluminum – magnesium silicate on Chloroquine phosphate against Plasmodium berghei. Nature precedings:hdt 10101/npre 20126749.1.posted 2 Jan.2012.   

 54.     Ezeibe, M. C. O.,Anosa,G.N.,Okorie,O.K., Elendu – Eleke,N. P.,Okoroafor, O. N, Ngene,A. A.and Chikelu, O. N.(2012).Aluminum – magnesium silicate enhances antibacterial activity of Ampicilline trihydrate,against S.gallinarum.Nature precedings:http:hdt.handle.net/10101/npre.2012.6814.1.posted 23 Jan.2012.

 55.     Sanda,M. E., Ezeibe,M. C. O. and Anene,B. M.(2012).Survey of Newcastle Disease immune levels of sellected poultry farms in Dekina Local Government Area of Kogi State, Nigeria.Nig. J.Fd. Drg. Hlth.5(1): 79 – 82.

 56.     Ezeibe, M. C . O. Okoye,J.O.A.,Ogunniran,T.M,Okoroafor,O.N,Ezeala,I.E and Ngene,A.A.(2012). Modification  of the Passive Heamagglutination  Test for  Detection  of  Infectious Bursal Disease Virus.Health 4(9): 653 – 655.

 57.     Ezeibe, M, C. O ,Dire, C.D, Anosa, G. N ,Chikelu, O. N, Okoroafor, O. N, Okorie, O. K., Ngene, A. A.,  Idika, I. K,Ogunniran,T. M.  and Ezeala, I. E (2012). Efficacy of Piparazine Citrate, stabilized with Aluminum – magnesium silicate, against  Helignosomoides bakeri. Health4(10) : 890-892.

 58.     Ezeibe,M. C. O., Chima,U. M., Ngene, A. A., Okoroafor, O. N.,Kalu,I.I and Esen, M. E.(2012).Effective treatment of  resistant Escherichia coliinfection, with Sulphadimidine stabilized in a synthetic Aluminum-magnesium silicate. Health4(12):1295-1298.

59.     Ezeibe, M. C. O.(2012). Highly pathogenic Avian Influenza Virus disease (Bird Flu)- Recommended control measure. JVAS  2(1): 8 – 14.

60.     Ezeibe, M. C. O., Animoke, P. C., Mbuko, I. J., Sanda, M. E., Nnoje, C., Okafor, U. C., Ngene, A. A. and Oguniran, T. O.(2012). Seroprevalence of Infectious bursal disease in day old chicks and immune response of chicks to vaccination against the disease.JVAS 2 (1): 36 -40.

61.     Ezeibe, M. C. O. ,Elendu-Eleke, N.P., Anyaora, U., Okoroafor, O.N.,Ngene,A.A.,Eze, J. I. and Ugonabo, J.A.C.(2012).Incidence of zoonotic helminth parasites in non-human primates at the zoological garden of University of Nigeria, Nsukka, South East Nigeria. JVAS 2(1): 45 – 48.

 62.     Ezeibe,M. C. O,Okoye, J. O. A, Ogunniran, T. M., Animoke, P.  C., Mbuko, I. J. ,NwankwoI. A and  Ngene,Augustine A(2013).Mortality rates from a Nigerian isolate of the Infectious Bursa Disease Virus and Passive haemagglutination  antibody titer that protects chicks against  challenge with the virus. Health 5(9):1355-1359.

 63.     Ezeibe, M. C. O., Ngene ,A. A. Anene, I.  Amechi, B. Olowoniyi ,P.Eze, J. I. and Animoke, P. C.(2013). Direct passive hemagglutination test for rapid quantification of plasma loads of the Human immunodeficiency Virus.Health 5(9):1351-1354.

 64.     Ezeibe, M. C. O., Ekeanyanwu, E.,  Ngene, A. A. and  Mbuko, I. J.(2013).

Aluminum-magnesium silicate enhances  release of virions  of cultured Fowlpox Virus  and inhibits the virus.Health.5(9):1394-1396.

 65.     Ezeibe, M. C. O., Ezeobele,O. K, Esen, M.E., Ngene, A. A., Mbuko, I. J. Chukwudi, I. C., Omoja, V. U. and Ezeh, I. O.(2013) Synergy in  antibacterial  activities of Ampicillin  trihydrate, stabilized with a synthetic Aluminum-magnesium silicate and immune-stimulants, on  resistant Escherichia coliinfection.Health 5(10): 1548 -1552.

 66.     Ezeibe,M. C. O.,Okoye, J. O. A.,Ogunniran, T. M., Animoke,P. C., Ijeoma. J. Mbuko,I. J.,Nwankwo, I. A and Ngene,A. A.(2014).Effects of live Infectious bursa disease .vaccines, on immune response of vaccinated chicks. BJMMR. 4(7) : 1506 - 1513.

 67.     Ezeibe, M. C. O., Ngene, A.A., Kalu,I.K., Ezeh, I. O., Mbuko, I.      J.,Ekwuruke,J.O., Anene,I.,Amechi,B.,Olowoniyi,P.andIfekwe, I.   F.(2014).Assessment of Antiretroviral effects of a synthetic Aluminum-          magnesium silicate. BJMMR 4(8) :1672 - 1679.

 68.    Ezeibe, M. C. O.,  Okoye, J. O. A,  Ezeala, I. E., Mbuko, I. J. and  Ngene, A.           A.(2014).Comparison of Agglutination of Mammalian erythrocytes plus heat        stability tests and agglutination of mammalian erythrocytes plus erythrocyte        elution time to a standard method, for characterizing field isolates of  Newcastle    disease virus.BMRJ, 4(7): 730-736.

 69.     Ezeibe, M. C. O., Okoye, J. O. A.,  Ezeala, I. E., Mbuko, I. J. and Ngene, A.       A.(2014). Strains  ofNewcastle disease virus circulating among sick poultry       flocks  in Nsukka, Nigeria.BMRJ5(4): 384-388,

 70.     Ezeibe, M.C.O. and Ogbonna, I.J. (2015).  Acquired Immune Deficiency   Syndrome in Man and Animals— A Review.  World Journal of AIDS,5, 50-57.

 71. Ezeibe, M.C.O. and Ogbonna, I.J. (2015). In vivo Antiretroviral Effects of the Medicinal Synthetic Aluminum-Magnesium Silicate. World Journal of AIDS, 5: 59-65.

 72. Ezeibe, M.C.O. and Ogbonna, I.J. (2015).Enhancing efficacy of antimicrobials with theMedicinal Synthetic Aluminum-Magnesium Silicate, for prevention and treatment of resistant Infections.BJMMR. 9(6): 1-8.

 73 .Sanda, M. ,Ezeibe, M. C. O. and Anene, B. M(2015). Effects of Vitamins A,  C and E and Sellenium on immune response of broilers to Newcastle vaccine. J. Agric.and Vet, sc 8(7):  13 – 15.

 74.Sanda, M. ,Ezeibe, M. C. O. and Anene, B. M(2015). Effect of Routes of Administration on Immune Response of Broiler Chicks to Newcastle Disease Vaccine (LaSota) J. Appl. Life Sc. Int3(3): 138-142.

 75.Ezeibe, M. C. O. and Ogbonna, I. J.(2016). Medicinal synthetic Aluminum-magnesium silicate{Al4(SiO4)3 + 3Mg2SiO4 → 2Al2Mg3(SiO4)3} – Ahighly activeanti-retroviral medicine. World Journal of AIDS, 6: 42-46.

 76.Ezeibe, M.C.O., Aleeyu, D., Ogbonna, I.J. and Kalu, E. (2016) Clinical Trial of Medicinal Synthetic Aluminum-Magnesium Silicate (Antivirt®) on Viral Loads and CD4-Lymphocytes Counts of HIV/AIDS Patients. World Journal of AIDS, 6: 37-41. http://dx.doi.org/10.4236/wja.2016.62005.

 77.Ezeibe, M.C.O,Aleeyu, D., Aneke, N.K., Obarezi, T.N., Ogbonna, I.J. and Kalu, E. (2016). Assessment of Antiretroviral Efficacy of the Medicinal Synthetic Aluminum-Magnesium Silicate {Al4(SiO4)3 + 3Mg2SiO4 → 2Al2Mg3(SiO4)3}.

World Journal of AIDS, 6, 74-80. http://dx.doi.org/10.4236/wja.2016.62011.

 78. Ezeibe, M. C. O.,  Aleeyu, D.  Aneke, N. K., Obarezi, T. N.,  Ogbonna1, I. J., Kalu,  E. and  Njoku, N. U.(2016).HIV/AIDS Recovery Rates in Male and FemalePatients, Treated with Medicinal synthetic Aluminum-magnesium silicate. BJMMR.18: 1-7.

79. Ezeibe, M. C. O.and Ogbonna, I. J.(2016).Use of the medicinal synthetic aluminum-magnesium silicate to enhance efficacy of antimicrobials, for prevention and treatment of resistant infections. Clin. Exp. Pharmacol.DOI: 10.4172/2161-1459.C1.010

 80. Ezeibe, M. C. O.,  Aleeyu, D.  Aneke, N. K., Obarezi, T. N.,  Ogbonna1, I. J.,  Kalu,  E. and  Njoku, N. U.(2017).Effective treatment of  HIV/AIDS                                   with medicinal  synthetic Aluminum-magnesium silicate

B. Books.

 

1. MaduikeEzeibe(2009). Culture and traditions of my people. Great Ap Express publishers Limited, Nsukka, Nigeria.

 2. MaduikeEzeibe(2017).Avian Newcastle disease: Ethical methods of characterizing the virus. Lambert academic publishing. Germany.

 3. MaduikeEzeibe(2017).The medicinal synthetic Aluminum-magnesium silicateScientific research publishing, USA.

 

C.      Patents

 1.   Ezeibe M.C.O. (2006).Admacine®. Federal Republic of Nigeria Patents and Designs Act.  Cap 344 LFN 1990, NO. RP 16446.

 2.Ezeibe M.C.O. (2006). Franccocine®. Federal Republic of Nigeria Patents and Designs Act.  Cap 344 LFN 1990, NO. RP 16447.

 3.Ezeibe M.C.O. (2006). Sal-travite®. Federal Republic of Nigeria Patents and Designs Act.  Cap 344 LFN 1990, NO. RP 16448.

 4.  Ezeibe, M.C.O. (2014). Medicinal synthetic Aluminum-magnesium silicate (Nanoparticles) – Antiviral agent and adjuvant to chemotherapeutics. Federal Republic of Nigeria Patents and Designs Ref No.: NG/P/2012/639.

5. Ezeibe M.C.O. Antivirt® (being processed).

 6. Ezeibe M.C.O. Ismercquine® (being processed).

 7. Ezeibe M.C.O. Bernazine® (being processed).